Express Scripts SafeGuardRx®
Our multi-program SafeGuardRxSM platform is continuously evolving to expose new opportunities in critical disease states.
Our Platform
SafeGuardRx combines our specialized clinical model and value-based contracting strategies to help plans improve patient care for the toughest conditions while also controlling costs.
Our Promise
SafeGuardRx unlocks increasingly greater clinical and financial value for plans and better outcomes for patients over time – providing a new peace of mind by reducing risk, cost and waste.
lives covered
specialty and chronic
classes covered
clinically appropriate,
cost-effective strategies
saved in 2018
SafeGuardRx Savings Calculator
It’s no secret that care for the most complex and challenging disease states must be improved and costs must be more effectively managed. SafeGuardRx is proven to do both in a single platform.
By enrolling in SafeGuardRx, you’re helping your members experience better medication adherence, higher therapy completion rates and greater compliance with clinical guidelines – without the risk, or concern, of the loss of financial value.
SafeGuardRxSM proves plans can achieve better health and increased savings
– without tradeoffs.
While others were still theorizing about solving healthcare’s toughest challenges, we got to work – applying our scale, rigor and tenacity to create a platform that is the best possible way for plans to deliver personalized care while keeping costs in check. Each year, SafeGuardRx delivers better outcomes and increased value. We continue to take on the most complex, highest-cost challenges in healthcare and, in 2018 alone, SafeGuardRx helped enrolled clients save more than $2.4 billion.
Click the icons to learn about the impact of the SafeGuardRx programs:
Click the arrows to learn about the impact of the SafeGuardRx programs:
Delivers personalized care for complex chronic and specialty conditions
Tackles market challenges to deliver lower overall costs
Helps lower the cost of
a cure for hepatitis C
Expands access to curative therapy to thousands of people
Delivers maximum value for PCSK9 inhibitors
Enrolled clients see lower costs per patient than those not enrolled
Aligns the cost of oncology medications with outcomes
Personalized medicine through genetic testing puts even more information in the patient’s and physician’s hands
Shields plans from the full cost impact of excessive year-over-year price increases on brand drugs
Leverages the power of our existing drug contracts to provide more value and budget predictability
Segments therapies by indication for inflammatory conditions to drive
to lower overall costs
Specialized care leads to lower therapy discontinuation rates
Motivates patients and delivers healthier outcomes through patient engagement technologies
High-touch support from Diabetes Therapeutic Resource
CenterSM clinicians
Protects against extreme price increases, unwarranted price discrepancies and patent expirations
Drives members to the most clinically appropriate, cost-effective therapies or dispensing channels
Delivers specialized clinical support and client savings due to increased adherence
Express Scripts shares your risk with early discontinuation reimbursements for preferred MS medications
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Unites specialized support and patient engagement tools for holistic management of asthma and COPD
Lowers net cost of treatment
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Protection from unexpected, staggering costs of rare conditions,
which affect 30M people in the U.S. – the same number battling diabetes
Guides patients with rare conditions to the most effective care pathway
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Drives savings on high-cost, breakthrough CGRP-inhibitor medications
Provides specialized clinical support through our Neuroscience Therapeutic Resource CenterSM
Watch VideoAt the heart of SafeGuardRx is our unwavering belief that within the most complex and expensive healthcare issues exists the greatest opportunity for improvement. We are working with participating plans to harness that opportunity through this platform. As Champions For Better, we take on the risk of managing clinical and financial challenges – and hold the entire healthcare marketplace accountable – in a way that others don’t, won’t or can’t.
To learn more about how SafeGuardRx can help you deliver better care and better value contact your Express Scripts account team or email us now.
