Express Scripts SafeGuardRx®

Making Medicine
Work Harder

Our multi-program, value-based platform unlocks new
financial value and better health outcomes.

Express Scripts SafeGuardRx®

Introducing the
HIV Care ValueSM Program

For more information about how HIV Care Value works,
download the Executive Brief.

Protection from health care’s
biggest budgetary threats

SafeGuardRx combines multiple effective cost-containment strategies into a single platform, and enrolled plans experience lower overall trend than nonenrolled plans.1

Condition-specific patient
engagement and support

Clients enrolled in SafeGuardRx see better patient medication adherence, higher therapy completion rates and greater compliance with clinical guidelines.1

56 million

lives covered

10

specialty and chronic
classes covered

Deploys

clinically appropriate,
cost-effective strategies

$4.3 billion

saved in 2019

SafeGuardRx Savings Calculator

Find out how much your plan could save with SafeGuardRx

Learn About the Savings You May Be Missing Out On

When medicine works harder,
our health care system works better

More potential and more health per dollar.
Year after year.

More than a product or a solution, SafeGuardRx is a promise and a platform to tackle difficult-to-manage conditions. SafeGuardRx combines specialized clinical support, condition-specific patient engagement tools and effective cost containment strategies.

This translates to lower downstream medical and prescription costs. That’s making medicine work harder.

Pioneering the Evolution of Care

While others were still theorizing about solving health care’s toughest challenges, we got to work – applying our scale, rigor and tenacity to create a platform that is the best possible way for plans to deliver personalized care while keeping costs in check. Each year, SafeGuardRx delivers better outcomes and increased value. We continue to take on the most complex, highest-cost challenges in health care and, in 2019 alone, SafeGuardRx helped enrolled clients save more than $4.3 billion.

Click the icons to learn about the impact of the SafeGuardRx programs:

Click the arrows to learn about the impact of the SafeGuardRx programs:

  • HIV CARE VALUESM
  • HEPATITIS CURE VALUE®
  • CARDIOVASCULAR CARE VALUE®
  • ONCOLOGY CARE VALUE®
  • INFLATION PROTECTION
  • INFLAMMATORY CONDITIONS CARE VALUESM
  • DIABETES CARE VALUESM
  • MARKET EVENTS PROTECTIONSM
  • MULTIPLE SCLEROSIS CARE VALUESM
  • PULMONARY CARE VALUESM
  • RARE CONDITIONS CARE VALUE®
  • MIGRAINE CARE VALUESM

Delivers personalized care for complex chronic and specialty conditions

Tackles market challenges
to deliver lower overall costs

  • Lowers cost unpredictability

    Delivers access to specialized clinical support

    Download Executive Brief
  • Helps lower the cost of
    a cure
    for hepatitis C

    Expands access to curative
    therapy to thousands of people

  • Takes a holistic approach to
    cardiovascular management

    Enrolled clients see lower
    costs per patient
    than those not
    enrolled

  • Aligns the cost of oncology
    medications with outcomes

    Personalized medicine through
    genetic testing
    puts even more information in the patient’s and physician’s hands

  • Shields plans from the
    full cost impact of excessive
    year-over-year price increases on brand drugs

    Leverages the power of our
    existing drug contracts to provide
    more value and budget predictability

  • Segments therapies by indication
    for inflammatory conditions to drive
    to lower overall costs

    Specialized care leads to
    lower therapy discontinuation rates

  • Motivates patients and delivers
    healthier outcomes through patient engagement technologies

    High-touch support from
    Diabetes Therapeutic Resource
    CenterSM clinicians

    Download Executive Brief
  • Protects against extreme price
    increases, unwarranted price discrepancies and patent expirations

    Drives members to the most
    clinically appropriate, cost-effective therapies or dispensing channels

  • Delivers specialized clinical
    support and client savings
    due to increased adherence

    Express Scripts shares your risk with early discontinuation reimbursements
    for preferred MS medications

    Download Infographic
  • Unites specialized support and
    patient engagement tools for holistic management of asthma and COPD

    Lowers net cost of treatment

    Download Infographic
  • Protection from unexpected,
    staggering costs
    of rare conditions,
    which affect 30M people in the U.S.
    – the same number battling diabetes

    Guides patients with rare conditions
    to the most effective care pathway

    Watch Video
  • Drives savings on high-cost,
    breakthrough CGRP-inhibitor
    medications

    Provides specialized clinical support
    through our Neuroscience
    Therapeutic Resource CenterSM

    Watch Video
  • SAFEGUARDRx PROGRAM

    Delivers personalized care for complex chronic and specialty conditions

    Tackles market challenges to deliver lower overall costs

  • HIV CARE VALUESM

    Lowers cost unpredictability

    Delivers access to specialized clinical support

    Download Executive Brief
  • HEPATITIS CURE VALUESM

    Helps lower the cost of
    a cure
    for hepatitis C

    Expands access to curative therapy to thousands of people

  • CARDIOVASCULAR CARE VALUESM

    Takes a holistic approach to cardiovascular management

    Enrolled clients see lower costs per patient than those not enrolled

  • ONCOLOGY CARE VALUESM

    Aligns the cost of oncology medications with outcomes

    Personalized medicine through genetic testing puts even more information in the patient’s and physician’s hands

  • INFLATION PROTECTIONSM

    Shields plans from the full cost impact of excessive year-over-year price increases on brand drugs

    Leverages the power of our existing drug contracts to provide more value and budget predictability

  • INFLAMMATORY CONDITIONS CARE VALUESM

    Segments therapies by indication for inflammatory conditions to drive
    to lower overall costs

    Specialized care leads to lower therapy discontinuation rates

  • DIABETES CARE VALUESM

    Motivates patients and delivers healthier outcomes through patient engagement technologies

    High-touch support from Diabetes Therapeutic Resource
    CenterSM clinicians

    Download Executive Brief
  • MARKET EVENTS PROTECTIONSM

    Protects against extreme price increases, unwarranted price discrepancies and patent expirations

    Drives members to the most clinically appropriate, cost-effective therapies or dispensing channels

  • MULTIPLE SCLEROSIS CARE VALUESM

    Delivers specialized clinical support and client savings due to increased adherence

    Express Scripts shares your risk with early discontinuation reimbursements for preferred MS medications

    Download Infographic
  • PULMONARY CARE VALUESM

    Unites specialized support and patient engagement tools for holistic management of asthma and COPD

    Lowers net cost of treatment

    Download Infographic
  • RARE CONDITIONS CARE VALUE®

    Protection from unexpected, staggering costs of rare conditions,
    which affect 30M people in the U.S. – the same number battling diabetes

    Guides patients with rare conditions to the most effective care pathway

    Watch Video
  • MIGRAINE CARE VALUESM

    Drives savings on high-cost, breakthrough CGRP-inhibitor medications

    Provides specialized clinical support through our Neuroscience Therapeutic Resource CenterSM

    Watch Video

Fulfilling Our Promise as Champions For Better

At the heart of SafeGuardRx is our unwavering belief that within the most complex and expensive health care issues exists the greatest opportunity for improvement. We are working with participating plans to harness that opportunity through this platform. As Champions For Better, we take on the risk of managing clinical and financial challenges – and hold the entire health care marketplace accountable – in a way that others don’t, won’t or can’t.

To learn more about how SafeGuardRx can help you deliver better care and better value contact your Express Scripts account team or email us now.